Set in the heart of Rome, the Casa Sant'Anna Hotel Rome is within a 10 minute walk from Forum Romanum, Monument to Vittorio Emanuele II and Quirinal Palace. The hotel is conveniently located for sightseeing in Rome with Temple of Concord within a 10 minute walk. Set in Vatican City, the hotel is a perfect base while in Rome.

The Casa Sant'Anna Hotel Rome's neighbourhood is known for its nightlife and you'll be spoilt for choice when it comes to dining and bar options.

The Casa Sant'Anna Hotel Rome is only a few steps from Rione Monti. Tours and other travel arrangements can be organized at the hotel's tour desk. Rome Ciampino Airport (CIA) is a 30 minute drive from the hotel. Church of Saint Charles at the Four Fountains, Pontifical Gregorian University and Teatro dell'Opera di Roma are within a 20-minute walk from the hotel.